Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

INHIBITORY EFFECT OF TNF$alpha; ANTIBODIES ON SYNOVIAL CELL INTERLEUKIN-1 PRODUCTION IN RHEUMATOID ARTHRITIS

F M Brennan · The Lancet · 1989 · 1.1K citations

Life Sciences, Clinical Sciences, Immunology +12

Inhibition of Osteoblast Differentiation by Tumor Necrosis Factor-α*

Linda Gilbert, Xiaofei He, Paul Farmer et al. · Endocrinology · 2000 · 550 citations · Full text

Medicine, Developmental Biology, Bone Metabolism +16

Inhibition of osteoblastic bone formation by nuclear factor-κB

Jia Chang, Zhuo Wang, Eric Tang et al. · Nature Medicine · 2009 · 470 citations · Full text

Medicine, Orthopaedic Surgery, Bone Metabolism +9

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

Se‐Ran Yang, Jessica Wright, Mark R. Bauter et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2006 · 390 citations

Life Sciences, Immunology, Molecular Biology +17