Intraprocedural Tissue Diagnosis During ERCP Employing a New Cytology Preparation of Forceps Biopsy (Smash Protocol)

Abstract

Immediate cytopathologic diagnosis at ERCP was established in 72% of patients presenting with suspected malignant biliary obstruction using a new cytological preparation of forceps biopsies. This approach to ERCP tissue sampling permits immediate diagnosis and avoids the need for subsequent procedures, adds little cost and time, and is safe to perform.