2,5-Disubstituted pyridines as potent GPR119 agonists

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

Hilary A. Overton, Adam J. Babbs, S. M. Doel et al. · Cell Metabolism · 2006 · 648 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

Zhi‐Liang Chu, Christopher J. Carroll, Jean Alfonso et al. · Endocrinology · 2008 · 380 citations

Life Sciences, Endocrinology, Physiology +17

Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

Takatoshi Soga, Takahide Ohishi, Tetsuo Matsui et al. · Biochemical and Biophysical Research Communications · 2004 · 374 citations

Life Sciences, Biochemistry, Cell Biology +14

A Role for β-Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucose-Dependent Insulin Release

Zhi‐Liang Chu, Robert M. Jones, Hongmei He et al. · Endocrinology · 2007 · 292 citations

Medicine, Endocrinology, Pharmacology +17

GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis

Lan Hong, Galya Vassileva, Aaron Corona et al. · Journal of Endocrinology · 2009 · 165 citations · Full text

Life Sciences, Endocrinology, Physiology +17