Detection and differential diagnosis of colon cancer by a cumulative analysis of promoter methylation

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.

M F Kane, Massimo Loda, Gretchen M. Gaida et al. · PubMed · 1997 · 1.5K citations

Life Sciences, Genetics, Oncology +17

COBRA: a sensitive and quantitative DNA methylation assay

Zhongguo Xiong, Peter W. Laird · Nucleic Acids Research · 1997 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

Shuji Ogino, Katsuhiko Nosho, Gregory J. Kirkner et al. · Gut · 2008 · 780 citations · Full text

Medicine, Genetics, Oncology +17

Cumulative Association of Five Genetic Variants with Prostate Cancer

Shusen Zheng, Jielin Sun, Fredrik Wiklund et al. · New England Journal of Medicine · 2008 · 633 citations · Full text

Life Sciences, Genetics, Oncology +13