Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties

Antinociceptive activity of narcotic agonist and partial agonist analgesics and other agents in the tail-immersion test in mice and rats

Robert D. E. Sewell · Neuropharmacology · 1976 · 231 citations

Tail-immersion Test, Partial Agonist Analgesics, Health Sciences +13

4,5,6,7‐Tetrahydro‐1<i>H</i>‐imidazo[4,5‐<i>c</i>]pyridine‐6‐carboxylic acids (spinacines)

S. KLUTCHKO, John C. Hodges, C. John Blankley et al. · Journal of Heterocyclic Chemistry · 1991 · 17 citations

N Im, Pictet‐spengler Reaction, Derivatives +12

Ring size preference in the intramolecular cyclisation of amines with esters. Synthesis of aminoacid derived hexahydropyrimidines and tetrahydroimidazoles

Richard Besse, Peter J. Garratt, Christopher Hobbs et al. · Tetrahedron · 1990 · 13 citations

Combinatorial Chemistry, Size Preference, Engineering +7

7-Heteroaryl-1,2,3,5-tetrahydroimidazol[2,1-b]quinazolin-2(1H)-one derivatives with cardiac stimulant activity

Andrew Bell, Simon F. Campbell, D. Allen Roberts et al. · Journal of Medicinal Chemistry · 1989 · 11 citations

Medicinal Chemistry, Heart Rate, Biochemistry +13