Concepedia

The prion protein requires cholesterol for cell surface localization

Sabine Gilch, Claudia Kehler, Hermann Schätzl

Molecular and Cellular Neuroscience · 2005 · 66 citations · 28 references

DOI

Concepts

References

28

Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components

Thomas Harder, Peter Scheiffele, Paul Verkade et al. · The Journal of Cell Biology · 1998 · 1.2K citations · Full text

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Cholesterol, lipid rafts, and disease

Kai Simons, Robert Ehehalt · Journal of Clinical Investigation · 2002 · 897 citations · Full text

, , +17

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive.

Byron Caughey, Gregory J. Raymond · Journal of Biological Chemistry · 1991 · 627 citations · Full text

, , +13

Cholesterol Is Required for Surface Transport of Influenza Virus Hemagglutinin

Patrick Keller, Kai Simons · The Journal of Cell Biology · 1998 · 550 citations · Full text

, , +17

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform [published erratum appears in J Cell Biol 1995 Jul;130(2):501]

Albert Taraboulos · The Journal of Cell Biology · 1995 · 539 citations · Full text

, , +17