Concepedia

A Convenient Synthetic Method of 2-Cyano-6-methoxybenzothiazole, –A Key Intermediate for the Synthesis of Firefly Luciferin

Yoshiaki Toya, Masaharu Takagi, Hisao Nakata, Nobutaka Suzuki, Minoru Isobe, Toshio Goto

Bulletin of the Chemical Society of Japan · 1992 · 26 citations · 5 references

DOI

Concepts

Abstract

Abstract The title compound was prepared in one step from commercially available 2-amino-6-methoxybenzothiazole by using the Sandmeyer cyanation reaction. The result enabled us to synthesize firefly luciferin effectively from this amino compound through three steps in 36% overall yield.

References

5

<b>The Structure and Synthesis of Firefly Luciferin</b>

Emil H. White, Frank McCapra, George F. Field · Journal of the American Chemical Society · 1963 · 292 citations

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Analogs of Firefly Luciferin

Emil H. White, Helmut Wörther, George F. Field et al. · The Journal of Organic Chemistry · 1965 · 77 citations

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A Convenient Synthetic Method of 2-Carbamoyl-6-methoxybenzothiazole, One of Intermediates for the Synthesis of Firefly Luciferin

Shûichi Seto, Kyozo Ogura, Yukio Nishiyama · Bulletin of the Chemical Society of Japan · 1963 · 32 citations · Full text

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Derivatives of 2-Amino-6-methoxybenzothiazole

C. G. Stuckwisch · Journal of the American Chemical Society · 1949 · 24 citations

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Investigations on Herbicides IV: The synthesis of 2,6‐dichlorobenzonitrile

H. Koopman · Recueil des Travaux Chimiques des Pays-Bas · 1961 · 18 citations

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