Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

Engineering, In Vivo Gene Therapy, Several Polycations +20

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

Jean Haensler, Francis C. Szoka · Bioconjugate Chemistry · 1993 · 1.2K citations

Tissue Engineering, Engineering, Polyamidoamine Cascade Polymers +21

Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

N.D. Sonawane, Francis C. Szoka, A.S. Verkman · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

Degradable Poly(β-amino esters):  Synthesis, Characterization, and Self-Assembly with Plasmid DNA

David M. Lynn, Róbert Langer · Journal of the American Chemical Society · 2000 · 898 citations

Engineering, Molecular Biology, Organic Chemistry +17

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

MX Tang, FC Szoka · Gene Therapy · 1997 · 801 citations

Dna Nanotechnology, Engineering, Natural Sciences +12