Nitrite converts 2-amino-α-carboline, an indirect mutagen, into 2-hydroxy-α-carboline, a non-mutagen and 2-hydroxy-3-nitroso-α-carboline, a direct mutagen

Spectrometric identification of organic compounds

Robert M. Silverstein, G. Clayton Bassler · Journal of Chemical Education · 1962 · 14.3K citations

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Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

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Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N-nitroso compounds

B. Spiegelhalder, Gerhard Eisenbrand, R. Preußmann · Food and Cosmetics Toxicology · 1976 · 598 citations

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S R Tannenbaum, M. Weisman, D. Fett · Food and Cosmetics Toxicology · 1976 · 388 citations

Dentistry, Nutrition, Human Nutrition +3

Nitrite and Nitrate Are Formed by Endogenous Synthesis in the Human Intestine

S R Tannenbaum, D. Fett, V. R. Young et al. · Science · 1978 · 288 citations

Medicine, Cancer Biology, Oncology +7