Anti-angiogenesis participates in antitumor effects of metronomic capecitabine on colon cancer

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

Benilde Jiménez, Olga V. Volpert, Susan E. Crawford et al. · Nature Medicine · 2000 · 1K citations

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OPTIMOX1: A Randomized Study of FOLFOX4 or FOLFOX7 With Oxaliplatin in a Stop-and-Go Fashion in Advanced Colorectal Cancer—A GERCOR Study

Christophe Tournigand, Andrés Cervantes, Arié Figer et al. · Journal of Clinical Oncology · 2006 · 805 citations

Medicine, Oncology, Pharmacology +15

Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial

Miriam Koopman, Ninja Antonini, Joep Douma et al. · The Lancet · 2007 · 631 citations

Medicine, Oncology, Pharmacology +12

Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: antitumor activity and correlation with vascular endothelial growth factor levels

Marco Colleoni, Andrea Rocca, Maria Teresa Sandri et al. · Annals of Oncology · 2002 · 502 citations · Full text

Medicine, Oncology, Pharmacology +17

Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells.

Francesco Bertolini, Saki Paul, Patrizia Mancuso et al. · PubMed · 2003 · 460 citations

Medicine, Oncology, Pharmacology +15