Accumulation of Mutant Neuroserpin Precedes Development of Clinical Symptoms in Familial Encephalopathy with Neuroserpin Inclusion Bodies

Probability-based protein identification by searching sequence databases using mass spectrometry data

David N. Perkins, Darryl Pappin, David M. Creasy et al. · Electrophoresis · 1999 · 8.2K citations

Structure of a serpin–protease complex shows inhibition by deformation

James A. Huntington, Randy J. Read, Robin W. Carrell · Nature · 2000 · 1.1K citations

Protein Chemistry, Protein Assembly, Natural Sciences +2

Improvement of an "In-Gel" Digestion Procedure for the Micropreparation of Internal Protein Fragments for Amino Acid Sequencing

Ulf Hellman, Christer Wernstedt, Jorge Gonez et al. · Analytical Biochemistry · 1995 · 754 citations

Protein Chemistry, Amino Acid, Protein Folding +12

Familial dementia caused by polymerization of mutant neuroserpin

Richard L. Davis, Antony E. Shrimpton, P D Holohan et al. · Nature · 1999 · 347 citations · Full text

Alzheimer's Disease, Dementia, Frontotemporal Dementia +6

Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice.

Joyce Carlson, Brianne B. Rogers, R N Sifers et al. · Journal of Clinical Investigation · 1989 · 324 citations · Full text

Autoimmune Disease, Medicine, Liver Physiology +14