Partial synthesis of tritium‐labelled gibberellin‐A₃

Abstract

Abstract The epimeric gibberellin‐A 3 ‐7‐aldehydes 1 and 2 were silylated, enolised with KH and labelled with 3 H 2 O to give after desilylation the tritium‐labelled epimeric gibberellin‐A 3 ‐7‐aldehydes 4 and 5 . Subsequent acetylation, oxidation and deacetylation afforded [6‐ 3 H] gibberellin‐A 3 ( 6 ) and [6‐ 3 H]6‐epi‐gibberellin‐A 3 ( 7 ). Thus, this route provides a convenient method for the preparation of [6‐ 3 H]GA 3 of high specific radioactivity.