Concepedia

Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

M Guillot, Sara Eisler, Kathrin Weller, Hans P. Merkle, Jean‐Louis Gallani, François Diederich

Organic & Biomolecular Chemistry · 2006 · 49 citations · 32 references

DOI

Concepts

Abstract

A library of novel amphiphilic, self-assembling dendrimers was designed and synthesised to evaluate the effects of structural changes on transfection efficiency.

References

32

Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes

Joachim O. Rädler, Ilya Koltover, Tim Salditt et al. · Science · 1997 · 1.4K citations · Full text

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

Jiin Felgner, Rajesh Kumar, Ch. Sridhar et al. · Journal of Biological Chemistry · 1994 · 1.3K citations · Full text

, , +21

Dendrimers:

N Malik, Ruedeekorn Wiwattanapatapee, Rainer Klopsch et al. · Journal of Controlled Release · 2000 · 1.2K citations

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

Jean Haensler, Francis C. Szoka · Bioconjugate Chemistry · 1993 · 1.2K citations

, , +21