Preparation of 7‐substituted pyrrolo [2,3‐<i>d</i>] pyrimidines and 9‐substituted purines as potential antiparasitic agents

Abstract

Abstract A series of six 7‐substituted pyrrolo [2, 3‐ d ] pyrimidines and two 9‐substituted purines were prepared and evaluated for potential antiparasitic activity. All were inactive against P. berghei in mice. Six of the target compounds were also evaluated for antitrypanosomal activity against T. rhodesiense in mice. All six compounds were also inactive in this screen.