Phosphatidylinositol 3-Kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.2K citations · Full text

Specific Inhibitor, Molecular Pharmacology, Medicinal Chemistry +16

Disruption of epithelial cell-matrix interactions induces apoptosis

SM Frisch, H. Francis · The Journal of Cell Biology · 1994 · 3.2K citations · Full text

Anchorage Independence, Cell Regulation, Tumor Microenvironment +15

The extracellular matrix as a cell survival factor.

Jere E. Meredith, Bahare Fazeli, Martin A. Schwartz · Molecular Biology of the Cell · 1993 · 1.5K citations

Undergo Pcd, Cell Signaling, Cell Adhesion +15

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

Nancy Boudreau, Carolyn J. Sympson, Zena Werb et al. · Science · 1995 · 1.2K citations · Full text

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

Gregory E. Hannigan, Chungyee Leung-Hagesteijn, L Fitz-Gibbon et al. · Nature · 1996 · 1.1K citations

Anchorage-dependent Growth, Developmental Biology, Signal Transduction +11