Changes in Hepatitis C Virus (HCV) Viral Load and Interferon-α Levels in HIV/HCV-Coinfected Patients Treated With Highly Active Antiretroviral Therapy

Abstract

Coinfected patients did not have evidence of hepatoxicity HAART. In patients with baseline HIV titer >10,000 copies/mL, suppression of HIV replication by HAART was associated with an increase in HCV titer and a decrease in endogenous IFN-alpha levels.