The role of tumor necrosis factor (TNF) in the febrile and metabolic responses of rats to intraperitoneal injection of a high dose of lipopolysaccharide

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

Kevin J. Tracey, Yuman Fong, David Hesse et al. · Nature · 1987 · 2.5K citations

Humoral Response, Immunology, Sepsis +5

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

Bruce Beutler, Ian W. Milsark, Anthony Cerami · Science · 1985 · 2.4K citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

H. R. Michie, Kirk R. Manogue, David R. Spriggs et al. · New England Journal of Medicine · 1988 · 1.7K citations

Immunology, Pathology, Inflammation +17

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

Terje Espevik · Journal of Immunological Methods · 1986 · 1.3K citations

Inflammation, Cytokine, Clone 13 +11

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

Joseph G. Cannon, Ronald G. Tompkins, Jeffrey A. Gelfand et al. · The Journal of Infectious Diseases · 1990 · 762 citations