Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin

T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells.

Hui Xu, Nancy A. Diiulio, Robert L. Fairchild · The Journal of Experimental Medicine · 1996 · 396 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Roles of thromboxane A2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice

Takuya Kobayashi, Yoshio Tahara, Mayumi Matsumoto et al. · Journal of Clinical Investigation · 2004 · 360 citations · Full text

Veterinary Medicine, Cell Biology, Pathobiology +17

CD4+ Th1 and CD8+ Type 1 Cytotoxic T Cells Both Play a Crucial Role in the Full Development of Contact Hypersensitivity

Binghe Wang, Hiroshi Fujisawa, Lihua Zhuang et al. · The Journal of Immunology · 2000 · 226 citations · Full text

Life Sciences, Cell Biology, Immunology +17

1‐Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti‐thrombotic activity mediated by a cyclooxygenase‐2/prostacyclin pathway

J Świȩs, Andrzej Mogielnicki, W Buczko et al. · British Journal of Pharmacology · 2007 · 198 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase

Rafał Olszanecki, E Marcinkiewicz, Roberto Motterlini · Cardiovascular Research · 2006 · 105 citations · Full text

Medicine, Biochemistry, Pharmacology +17