The expected effect of a combination of agents: the general solution

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

THE TOXICITY OF POISONS APPLIED JOINTLY1

C. I. Bliss · Annals of Applied Biology · 1939 · 2.4K citations

Pharmacy, Pharmacology, Toxicology +15

A Method for Testing for Synergy with Any Number of Agents

M. C. Berenbaum · The Journal of Infectious Diseases · 1978 · 734 citations

Medicine, Microbiology, Pharmacology +13

The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx

Kenneth J. Rothman, Andrew Z. Keller · Journal of Chronic Diseases · 1972 · 518 citations

Dentistry, Oral Biology, Oral Pathology +12

Generalized Equations for the Analysis of Inhibitions of Michaelis-Menten and Higher-Order Kinetic Systems with Two or More Mutually Exclusive and Nonexclusive Inhibitors

Ting‐Chao Chou, Paul Talalay · European Journal of Biochemistry · 2005 · 424 citations · Full text

Life Sciences, Biochemistry, Chemical Kinetics +14