Cerebral endothelial cell culture I. The presence of β2 and α2-adrenergic receptors linked to adenylate cyclase activity

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

The Concept of a Blood-Brain Barrier

General Pharmacology The Vascular System · 1980 · 792 citations

Medicine, Neurosurgery, Pharmacology +16

The Concept of a Blood-Brain Barrier

Jonathon S. Dunn · Journal of Neurology Neurosurgery & Psychiatry · 1980 · 379 citations · Full text

Medicine, Neurosurgery, Pharmacology +16

Regulation of adenylate cyclase of neuroblastoma x glioma hybrid cells by alpha-adrenergic receptors. I. Inhibition of adenylate cyclase mediated by alpha receptors.

Steven L. Sabol, Marshall W. Nirenberg · Journal of Biological Chemistry · 1979 · 289 citations · Full text

Medicine, Neurobiology, Pharmacology +14

Histamine-sensitive adenylate cyclase in mammalian brain

Linda R. Hegstrand, Philip D. Kanof, Paul Greengard · Nature · 1976 · 217 citations

Life Sciences, Neurobiology, Pharmacology +10