Characterization of [3H]naltrindole binding to delta opioid receptors in rat brain

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

Philip S. Portoghese, Marjia Sultana, A.E. Takemori · European Journal of Pharmacology · 1988 · 613 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Design of peptidomimetic .delta. opioid receptor antagonists using the message-address concept

P. S. Portoghese, Marjia Sultana, A.E. Takemori · Journal of Medicinal Chemistry · 1990 · 259 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Deltorphin, a novel amphibian skin peptide with high selectivity and affinity for δ opioid receptors

Günther Kreil, Donatella Barra, Maurizio Simmaco et al. · European Journal of Pharmacology · 1989 · 233 citations

Medicine, Neuroscience, Pharmacology +15

Differential cardiovascular and respiratory responses to central administration of selective opioid agonists in conscious rabbits: correlation with receptor distribution

Clive N. May, Michael R. Dashwood, C.J. Whitehead et al. · British Journal of Pharmacology · 1989 · 86 citations · Full text

Medicine, Neuroscience, Pharmacology +17