Philippine Journal of Internal Medicine · 2010 · 10 citations · 3 references
MedicineEndocrinologySurgeryEndocrine OncologyEndocrine SurgeryNeuroendocrinologyDiabetes MellitusHormone-secreting TumorsPituitary DisordersPituitary Gland FunctionPituitary SurgeryPituitary TumorsFunctioning Pituitary AdenomasPituitary Adenoma EndocrinologyPituitary Adenoma SurgeryPituitary DysfunctionPituitary InvolvementPituitary PathologyPituitary Tumor-related Visual LossProlactinoma Surgery
Results: Data of forty one patients (23 males, 18 females; mean age: 42 years, range: 19-68) were reviewed. Majority have clinically non functioning tumors (n=17), fol lowed by prolactinoma (n=12) and acromegaly (n=7). E ighty s ix percent were macroadenomas. Transphenoidal surgery (TSS) was the main treatment in 70% of patients (n=28) while dopamine agonist was used in another 28% (n=11). Diabetes insipidus occurred in 24% of cases. One patient died of hospital acquired pneumonia. Thirty one patients were evaluated after a mean of 1.4 years (range: 0.25 3.9 years). There was a decrease in visual disturbances (73 to 23%), headache (63 to 6%), signs and symptoms of hypogonadism (38 to 19%) and hypopituitarism (60 to 52%) before and after treatment, respectively. Hormonal control was achieved in 71% while radiological cure was achieved in 35%.
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