Concepedia

A novel epidermal growth factor receptor variant lacking multiple domains directly activates transcription and is overexpressed in tumors

Emilio Piccione, Thuan Lieu, Chris Gentile, Thomas Robert Williams, Andrew J. Connolly, Andrew K. Godwin, Albert C. Koong, Albert J. Wong

Oncogene · 2011 · 21 citations · 53 references

DOI

Concepts

References

53

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et al. · New England Journal of Medicine · 2004 · 11.5K citations

, , +16

<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

J. Guillermo Paez, Pasi A. Jänne, Jeffrey C. Lee et al. · Science · 2004 · 9.4K citations

, , +17

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

, , +13

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.3K citations

, , +10

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

, , +15