Lymphocyte content of amyloid precursor protein is increased in Down's syndrome and aging

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Robin Sherrington, Yuh‐Jin Liang, Ekaterina Rogaeva et al. · Nature · 1995 · 4K citations

Life Sciences, Genetics, Molecular Genetics +14

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

Life Sciences, Molecular Biology, Neurology +16

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

Andreas Weidemann, Gerhard König, Dirk Bunke et al. · Cell · 1989 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +12