Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN)

Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.

HAMAO UMEZAWA, TAKAAKI AOYAGI, Suda Hiroyuki et al. · The Journal of Antibiotics · 1976 · 721 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

Role of aminopeptidase N (CD13) in tumor‐cell invasion and extracellular matrix degradation

Ikuo Saiki, Junya Yoneda, Ichiro Azuma et al. · International Journal of Cancer · 1993 · 343 citations · Full text

Medicine, Cell Biology, Oncology +10

Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes

Daniel H. Rich, Byung Jo Moon, Scott L. Harbeson · Journal of Medicinal Chemistry · 1984 · 220 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis

Kazuteru Fukasawa, Hideji Fujii, Yurika Saitoh et al. · Cancer Letters · 2006 · 140 citations

Life Sciences, Cell Biology, Molecular Biology +10

Impaired angiogenesis in aminopeptidase N-null mice

Roberto Rangel, Yan Sun, Liliana Guzman‐Rojas et al. · Proceedings of the National Academy of Sciences · 2007 · 127 citations · Full text

Medicine, Cell Biology, Molecular Biology +13