Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase C-dependent

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg et al. · New England Journal of Medicine · 1994 · 3.8K citations · Full text

Medicine, Ophthalmology, Vision Science +15

Vascular Endothelial Growth Factor–Induced Retinal Permeability Is Mediated by Protein Kinase C In Vivo and Suppressed by an Orally Effective β-Isoform–Selective Inhibitor

Lloyd Paul Aiello, Sven–Erik Bursell, Allen C. Clermont et al. · Diabetes · 1997 · 669 citations

Medicine, Ophthalmology, Pharmacology +15

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.

Pu Xia, Lloyd Paul Aiello, Hideki Ishii et al. · Journal of Clinical Investigation · 1996 · 570 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Advanced glycation end products increase retinal vascular endothelial growth factor expression.

Ming Y. Lu, Manabu Kuroki, Seiji Amano et al. · Journal of Clinical Investigation · 1998 · 423 citations · Full text

Life Sciences, Biochemistry, Ophthalmology +11

Glucose-Induced Protein Kinase C Activation Regulates Vascular Permeability Factor mRNA Expression and Peptide Production by Human Vascular Smooth Muscle Cells In Vitro

Bryan Williams, Barbara Gallacher, Hashmukh Patel et al. · Diabetes · 1997 · 280 citations

Life Sciences, Cell Biology, Molecular Biology +15