METABOLIC ADAPTATIONS TO A “STUFF AND STARVE” FEEDING PROGRAM. II. OBESITY AND THE PERSISTENCE OF ADAPTIVE CHANGES IN ADIPOSE TISSUE AND LIVER OCCURRING IN RATS LIMITED TO A SHORT DAILY FEEDING PERIOD*

Abstract

Many obese people who want to lose weight seem unable to follow diets which will allow them to achieve and maintain ideal weight (1-3). This failure to follow diets has been ascribed to a lack of interest or to psychological factors, since no clear-cut abnormality in so-called simple or exogenous obesity other than excessive food in- take has been delineated (4).