Concepedia

BMP15 Prevents Cumulus Cell Apoptosis Through CCL2 and FBN1 in Porcine Ovaries

Bo Zhai, Huiyu Liu, Li Xu, Lisheng Dai, Yan Gao, Changhong Li, Lianjiang Zhang, Yu‐Qiang Ding, Xianfeng Yu, Jiabao Zhang

Cellular Physiology and Biochemistry · 2013 · 63 citations · 21 references

DOIFull text

Open access

Abstract

The results obtained in this study firstly demonstrated that CCL2 and FBN1 are important regulatory factors of BMP15 in preventing cumulus cell apoptosis in porcine ovaries.

References

21

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

, , +6

Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene

Harry C. Dietz, Carry Cutting, Reed E. Pyeritz et al. · Nature · 1991 · 2K citations

, , +8

Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome

Enid Neptune, Pamela A. Frischmeyer, Dan E. Arking et al. · Nature Genetics · 2003 · 1.4K citations

, , +8

Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner

Susan Galloway, Kenneth P. McNatty, Lisa Cambridge et al. · Nature Genetics · 2000 · 1.1K citations

, , +12

Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis

Kentaro Akiyama, Chider Chen, Dandan Wang et al. · Cell stem cell · 2012 · 685 citations · Full text

, , +7