PLoS ONE · 2013 · 23 citations · 37 references
The MaMV vaccine platform triggered an improved immune response directed towards the universal M2e peptide. The adjuvant OmpC increased the immune response to the M2e peptide and protection to a heterosubtypic influenza strain that harbors a different M2e peptide in a mouse model. Antibodies generated by the vaccine formulation showed cross-reactivity with M2e peptides derived from influenza strains H9N2, H5N1 and H1N1. The vaccine formulation shows a potential for commercialization of a new M2e based vaccine in dogs.
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Transmission of Equine Influenza Virus to Dogs
P.C. Crawford, Edward J. Dubovi, William L. Castleman et al. · Science · 2005 · 642 citations