Aberrant DNA methylation of the transcription factor C/EBPα in acute myelogenous leukemia

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial

David Grimwade, Helen M. Walker, Fiona Oliver et al. · Blood · 1998 · 2.6K citations · Full text

Life Sciences, Hematology, Oncology +12

Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia

Peter J.M. Valk, Roel G.W. Verhaak, M. Antoinette Beijen et al. · New England Journal of Medicine · 2004 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

Thomas Pabst, Beatrice U. Mueller, Pu Zhang et al. · Nature Genetics · 2001 · 909 citations

Life Sciences, Genetics, Molecular Biology +12

Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms

Steven D. Gore, Stephen B. Baylin, Elizabeth A. Sugar et al. · Cancer Research · 2006 · 472 citations · Full text

Medicine, Oncology, Pharmacotherapy +17