Ketanserin and pirenperone attenuate acute morphine withdrawal in rats

Statistical Principles in Experimental Design

Jerome L. Myers, B. J. Winer · The American Journal of Psychology · 1964 · 8.1K citations

Public Health, Biostatistics, Experimental Design +10

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

The head-twitch response to intraperitoneal injection of 5-hydroxytryptophan in the rat: Antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, an LSD antagonist

Françis C. Colpaert, Paul A. J. Janssen · Neuropharmacology · 1983 · 122 citations

Medicine, Neuroscience, Pharmacology +11

Mescaline‐induced head‐twitches in the rat: An in vivo method to evaluate serotonin S₂ antagonists

C. J. E. Niemegeers, Françis C. Colpaert, J.E. Leysen et al. · Drug Development Research · 1983 · 58 citations

Medicine, Neuroscience, Pharmacology +12