Concepedia

HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis

Sari Karlsson, Ville Pettilä, Jyrki Tenhunen, Raili Laru‐Sompa, Marja Hynninen, Esko Ruokonen

Intensive Care Medicine · 2008 · 160 citations · 32 references

Concepts

Veterinary MedicineImmunologyMolecular MedicineInflammationInnate ImmunitySepsisAcute Respiratory Distress SyndromeBiomarkers In SepsisSepsis ManagementSepsis PathophysiologySepsis PrognosisSeptic ShockOrgan Dysfunction PredictionSepsis Severity StratificationSepsis-associated InflammationSepsis-associated Organ FailureSepsis-induced Organ Failure

References

32

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

Medicine, Internal Medicine, Clinical Classification Systems +16

APACHE II-A Severity of Disease Classification System

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

Health Professions, Biostatistics, Clinical Classification Systems +12

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker et al. · Critical Care Medicine · 2001 · 8.6K citations

Veterinary Medicine, Infectious Diseases, Internal Medicine +16

A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

J. R. Le Gall · JAMA · 1993 · 6.4K citations

Medicine, Internal Medicine, Acute Care Medicine +9

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre et al. · New England Journal of Medicine · 2001 · 6.1K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13