Transgenic RNAi-mediated reduction of MSY2 in mouse oocytes results in reduced fertility

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Cell Biology, Pharmacology +15

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

Jonathan Lytton, Marisa M. Westlin, Michael R. Hanley · Journal of Biological Chemistry · 1991 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

Hiroaki Tabara, Madathia Sarkissian, William G. Kelly et al. · Cell · 1999 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

An improved culture medium supports development of random-bred 1-cell mouse embryos <i>in vitro</i>

Clare L. Chatot, Carol A. Ziomek, B. D. Bavister et al. · Reproduction · 1989 · 1.1K citations · Full text

Life Sciences, Biology, Developmental Biology +11

Specific interference with gene function by double-stranded RNA in early mouse development

Florence Wianny, Magdalena Zernicka‐Goetz · Nature Cell Biology · 1999 · 722 citations

Life Sciences, Developmental Biology, Genetics +10