Science · 2008 · 1.3K citations · 24 references
Natural SciencesMaterials EngineeringMaterials ScienceBiomedical ImagingMaterials ChemistryOpticsX-ray CrystallographyX-ray Data AnalysisX-ray DiffractionX-ray OpticsDiffraction PatternsHigh-resolution X-ray DiffractionHigh-resolution X-ray ImagingMicroscopyMicroscopy ImagingNanometer-scale Imaging
Coherent diffractive imaging and scanning transmission X‑ray microscopy are popular techniques, with CDI offering sub‑10‑nm resolution at the cost of stringent data quality, while STXM provides simpler analysis but is limited by spot size. The study demonstrates a ptychographic imaging method that bridges the gap between CDI and STXM. It records complete diffraction patterns at each point of a STXM scan. The high penetration power of X‑rays combined with high spatial resolution will allow investigation of complex mesoscopic life and material science specimens, such as embedded semiconductor devices or cellular networks.
Coherent diffractive imaging (CDI) and scanning transmission x-ray microscopy (STXM) are two popular microscopy techniques that have evolved quite independently. CDI promises to reach resolutions below 10 nanometers, but the reconstruction procedures put stringent requirements on data quality and sample preparation. In contrast, STXM features straightforward data analysis, but its resolution is limited by the spot size on the specimen. We demonstrate a ptychographic imaging method that bridges the gap between CDI and STXM by measuring complete diffraction patterns at each point of a STXM scan. The high penetration power of x-rays in combination with the high spatial resolution will allow investigation of a wide range of complex mesoscopic life and material science specimens, such as embedded semiconductor devices or cellular networks.
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Femtosecond diffractive imaging with a soft-X-ray free-electron laser
Henry N. Chapman, Anton Barty, Michael J. Bogan et al. · Nature Physics · 2006 · 1K citations · Full text
Natural Sciences, Physics, Optics +12
Hard-X-Ray Lensless Imaging of Extended Objects
J. M. Rodenburg, A C Hurst, A. G. Cullis et al. · Physical Review Letters · 2007 · 846 citations · Full text