Microtiter Plate Assays for Inhibition of Human, Drug-Metabolizing Cytochromes P450

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Allan E. Rettie, Kenneth R. Korzekwa, Kent L. Kunze et al. · Chemical Research in Toxicology · 1992 · 602 citations

Medicine, Pharmacology, Toxicology +17

Differential effects of phenobarbitone and 3-methylcholanthrene induction on the hepatic microsomal metabolism and cytochrome P-450-binding of phenoxazone and a homologous series of its n-alkyl ethers (alkoxyresorufins)

M.D. Burke, Richard T. Mayer · Chemico-Biological Interactions · 1983 · 327 citations

Medicine, Biochemistry, Pharmacology +16

A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

M. Teresa Donato, M. José Gómez‐Lechón, José V. Castell · Analytical Biochemistry · 1993 · 300 citations

Medicine, Biochemistry, Pharmacology +11

Simultaneous Measurement of Cytochrome P4501A Catalytic Activity and Total Protein Concentration with a Fluorescence Plate Reader

Sean W. Kennedy, Stephanie P. Jones · Analytical Biochemistry · 1994 · 299 citations

Life Sciences, Biochemistry, Pharmacology +12

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

Sandra Baldwin, J. C. Bloomer, Graeme Smith et al. · Xenobiotica · 1995 · 298 citations

Medicine, Biochemistry, Pharmacology +17