Metabolism of Flavonoids via Enteric Recycling: Mechanistic Studies of Disposition of Apigenin in the Caco-2 Cell Culture Model

Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells

Sanjay Gupta, Farrukh Afaq, Hasan Mukhtar · Oncogene · 2002 · 296 citations

Life Sciences, Cell Biology, Molecular Biology +16

Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human β-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism

Karen O’Leary, Andrea J. Day, Paul W. Needs et al. · Biochemical Pharmacology · 2003 · 270 citations

Pharmacy, Biochemistry, Pharmacology +11

Cell-Cycle Arrest at G2/M and Growth Inhibition by Apigenin in Human Colon Carcinoma Cell Lines

Weiqun Wang, Laura J. Heideman, Chilly S. Chung et al. · Molecular Carcinogenesis · 2000 · 269 citations

Medicine, Oncology, Pharmacology +17

Selective Growth-Inhibitory, Cell-Cycle Deregulatory and Apoptotic Response of Apigenin in Normal versus Human Prostate Carcinoma Cells

Sanjay Gupta, Farrukh Afaq, Hasan Mukhtar · Biochemical and Biophysical Research Communications · 2001 · 269 citations

Medicine, Cell Biology, Oncology +16

Absorption and Metabolism of Flavonoids in the Caco-2 Cell Culture Model and a Perused Rat Intestinal Model

Yan Liu, Ming Hu · Drug Metabolism and Disposition · 2002 · 253 citations

Pharmacy, Biochemistry, Pharmacology +13