Concepedia

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

Patrick Brest, Pierre Lapaquette, Mouloud Souidi, Kévin Lebrigand, Annabelle Césaro, Valérie Vouret‐Craviari, Bernard Mari, Pascal Barbry, Jean‐François Mosnier, Xavier Hébuterne,

Nature Genetics · 2011 · 561 citations · 23 references

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23

MicroRNA-155 is induced during the macrophage inflammatory response

Ryan M. O’Connell, Konstantin D. Taganov, Mark Boldin et al. · Proceedings of the National Academy of Sciences · 2007 · 1.8K citations · Full text

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Ken Cadwell, John Y. Liu, Sarah L. Brown et al. · Nature · 2008 · 1.5K citations · Full text

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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Miles Parkes, Jeffrey C. Barrett, Natalie J. Prescott et al. · Nature Genetics · 2007 · 1.2K citations · Full text

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Sequence Variants in <i>SLITRK1</i> Are Associated with Tourette's Syndrome

Jesse F. Abelson, Kenneth Y. Kwan, Brian J. O’Roak et al. · Science · 2005 · 946 citations

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Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria

Sudha Singh, Alexander S. Davis, Gregory A. Taylor et al. · Science · 2006 · 906 citations

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