Synthetic Communications · 1991 · 10 citations · 4 references
Carboxylic Acidsα-Bromo ThiolestersEngineeringBiochemistryEnantioselective SynthesisNatural SciencesDiversity-oriented SynthesisAbstract Carboxylic AcidsOrganic ChemistryHell-volhard-zelinsky ReactionChemistryStereoselective SynthesisNatural Product SynthesisSynthetic ChemistryCorresponding α-Bromo ThiolestersBiomolecular EngineeringConvenient Procedure
Abstract Carboxylic acids can be conveniently transformed to the corresponding α-bromo thiolesters by a one-pot procedure involving Hell-Volhard-Zelinsky reaction and trapping the α-bromo acyl bromide intermediate with mercaptans.
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