Concepedia

Publication | Open Access

Induction of Heme Oxygenase-1 Can Halt and Even Reverse Renal Tubule-Interstitial Fibrosis

DOIFull Paper Access

70

Citations

43

References

2010

Year

Matheus Corrêa-Costa, Patrícia Semedo, Ana Paula F. S. Monteiro, Reinaldo Correia Silva, Rafael Luiz Pereira, Giselle Martins Gonçalves, Georgia Daniela Marcusso Marques, Marcos Antônio Cenedeze, Ana Carolina Guimarães Faleiros, Alexandre C. Keller,
PLoS ONE

Abstract

Treatment with Hemin was able both to prevent the progression of fibrosis and to reverse an established renal scar. Modulation of inflammation appears to be the major mechanism behind HO-1 cytoprotection.

References

YearCitations

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