Concepedia

Beneficial Effect of Interleukin 1 Inhibition with Anakinra in Adult-onset Still’s Disease. An Open, Randomized, Multicenter Study

Dan Nordström, Ann Knight, Reijo Luukkainen, Ronald van Vollenhoven, Vappu Rantalaiho, ANNA KAJALAINEN, Johan G. Brun, Anne Prøven, Lotta Ljung, Hannu Kautiainen,

The Journal of Rheumatology · 2012 · 159 citations · 12 references

DOIFull text

Open access

Abstract

Anakinra induced more beneficial responses than DMARD in patients with AOSD and was favored in the OLE phase. (ClinicalTrials.gov Protocol Registration NCT01033656).

References

12

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Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

Virginia Pascual, Florence Allantaz, Edsel Arce et al. · The Journal of Experimental Medicine · 2005 · 911 citations · Full text

Rapid responses to anakinra in patients with refractory adult‐onset Still's disease

Avril A. Fitzgerald, Sharon LeClercq, Alexander Yan et al. · Arthritis & Rheumatism · 2005 · 347 citations

Tumour necrosis factor α blocking agents in refractory adult Still's disease: an observational study of 20 cases

Bruno Fautrel · Annals of the Rheumatic Diseases · 2004 · 217 citations · Full text

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Jeong‐Hee Choi, Chang‐Hee Suh, Young Mok Lee et al. · PubMed · 2003 · 198 citations