Age-dependent effects of nongenotoxic hepatocarcinogens on liver apoptosis in vivo

Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms

Peter A. Hall, David A. Levison, Amanda L. Woods et al. · The Journal of Pathology · 1990 · 1.5K citations

Veterinary Medicine, Oncology, Pathology +16

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

Paul B. Lazarow, C. De Duve · Proceedings of the National Academy of Sciences · 1976 · 1.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)

R. Roberts · Carcinogenesis · 1998 · 142 citations

Life Sciences, Molecular Biology, Pharmacology +17

Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously.

B Kraupp-Grasl, Wolfgang Huber, H Taper et al. · PubMed · 1991 · 97 citations

Medicine, Pharmacology, Toxicology +16

Non-genotoxic hepatocarcinogenesis stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations

Ruth Roberts, Anthony R. Soames, Jason H. Gill et al. · Carcinogenesis · 1995 · 97 citations

Pharmacy, Pharmacology, Toxicology +16