Suppression of collagen‐induced arthritis by single administration of poly(lactic‐co‐glycolic acid) nanoparticles entrapping type II collagen: A novel treatment strategy for induction of oral tolerance

Abstract

Our data show that PLGA may serve as a powerful vehicle to promote the tolerance effect of oral CII and that single administration of PLGA-CII may hold promise as a new treatment strategy in rheumatoid arthritis.