Concepedia

Catalytic Conversion of Nitriles into Secondary‐ and Tertiary Amides

Simge Davulcu, C. Liana Allen, Kirstie Milne, Jonathan M. J. Williams

ChemCatChem · 2012 · 20 citations · 27 references

DOI

Concepts

Abstract

A nice couple: The coupling of nitriles with amines in the presence of water is catalyzed by a combination of zinc triflate and hydroxylamine hydrochloride to give the corresponding amides in good yields.

References

27

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Stephen D. Roughley, Allan M. Jordan · Journal of Medicinal Chemistry · 2011 · 2.7K citations

, , +7

Key green chemistry research areas—a perspective from pharmaceutical manufacturers

David J. C. Constable, Peter J. Dunn, John Hayler et al. · Green Chemistry · 2007 · 1.5K citations

, , +17

Direct Synthesis of Amides from Alcohols and Amines with Liberation of H <sub>2</sub>

Chidambaram Gunanathan, Yehoshoa Ben‐David, David Milstein · Science · 2007 · 1.3K citations

, , +13

Palladium-Catalyzed Carbonylation—A Reaction Come of Age

C. F. J. Barnard · Organometallics · 2008 · 636 citations

, , +13

Developing artificial hydrolytic metalloenzymes by a unified mechanistic approach

Jik Chin · Accounts of Chemical Research · 1991 · 471 citations

, , +10