Bimodal effects of MK-801 on locomotion and stereotypy in C57BL/6 mice

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

J.S. Kim, H. H. Kornhuber, W. Schmid‐Burgk et al. · Neuroscience Letters · 1980 · 698 citations

Medicine, Neuroscience, Psychiatry +14

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

Maria Carlsson, Arvid Carlsson · Journal of Neural Transmission · 1989 · 426 citations

Life Sciences, Neuroscience, Pharmacology +16

Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia.

D. Javitt · PubMed · 1987 · 241 citations

Medicine, Pharmacology, Psychiatry +17

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting et al. · Drug Development Research · 1982 · 230 citations

Medicine, Neuroscience, Pharmacology +17