Evaluation of viral and mammalian promoters for driving transgene expression in mouse liver

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

F Liu, Young Song, D Liu · Gene Therapy · 1999 · 1.7K citations

Life Sciences, Biotechnology, Molecular Biology +15

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

Joan Boyes, Adrian Bird · Cell · 1991 · 729 citations

Life Sciences, Genetics, Molecular Biology +12

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

Cristina Rodríguez‐Antona, M. Teresa Donato, Alan R. Boobis et al. · Xenobiotica · 2002 · 417 citations

Medicine, Biochemistry, Molecular Biology +12

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.

Shioko Kimura, M Umeno, Radek C. Skoda et al. · PubMed · 1989 · 407 citations

Medicine, Genetics, Molecular Genetics +12

Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle

Alan R. Brooks, Richard N. Harkins, Peiyin Wang et al. · The Journal of Gene Medicine · 2004 · 372 citations

Life Sciences, Genetics, Molecular Genetics +16