Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo

A new technique for the assay of infectivity of human adenovirus 5 DNA

Frank L. Graham, A.J. van der Eb · Virology · 1973 · 9.7K citations

Life Sciences, Infectious Diseases, Molecular Biology +10

Biodegradable Long-Circulating Polymeric Nanospheres

Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science · 1994 · 2.9K citations

Pharmacy, Biomedical Engineering, Pharmaceutics +17

Controlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres

Smadar Cohen, Toshio Yoshioka, Melissa Lucarelli et al. · Pharmaceutical Research · 1991 · 845 citations

Pharmacy, Biomedical Engineering, Pharmaceutics +14

A model system for in vivo gene transfer into the central nervous system using an adenoviral vector

Beverly L. Davidson, Edward D. Allen, Karen Kozarsky et al. · Nature Genetics · 1993 · 579 citations

Life Sciences, Molecular Biology, Neuroscience +17

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo.

S H Chen, H. David Shine, J. Clay Goodman et al. · Proceedings of the National Academy of Sciences · 1994 · 481 citations

Medicine, Cancer Biology, Oncology +17