Concepedia

Design and synthesis of fluorescent SGLT2 inhibitors

Mark I. Lansdell, Denise J. Burring, David Hepworth, Matthew Strawbridge, Emily J. S. Graham, Thierry Guyot, Mark S. Betson, James D. Hart

Bioorganic & Medicinal Chemistry Letters · 2008 · 12 citations · 24 references

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References

24

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 628 citations · Full text

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The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Y. Kanai, W S Lee, Dennis Brown et al. · Journal of Clinical Investigation · 1994 · 624 citations · Full text

, , +15

The sodium/glucose cotransport family SLC5

Ernest M. Wright, Eric Turk · Pflügers Archiv - European Journal of Physiology · 2004 · 534 citations · Full text

, , +6

Molecular Analysis of the SGLT2 Gene in Patients with Renal Glucosuria

René Santer, Martina Kinner, C.L. Lassen et al. · Journal of the American Society of Nephrology · 2003 · 300 citations

, , +17

Sergliflozin, a Novel Selective Inhibitor of Low-Affinity Sodium Glucose Cotransporter (SGLT2), Validates the Critical Role of SGLT2 in Renal Glucose Reabsorption and Modulates Plasma Glucose Level

Kenji Katsuno, Yoshikazu Fujimori, Yukiko Takemura et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 266 citations

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