Structure odour studies with nitrogen derivatives of diterpene-derived acetals

Abstract

The nitrogen derivatives (6) and (7) of the perfumery acetals (2) and (3) have been synthesized from manool (1) by the Beckmann rearrangement of the oxime (10). The azo derivative (18),possessing the bridged ring system of the acetals, was synthesized by an intramolecular Lewis-acid catalysed cyclization of the tosylhydrazone (17).