Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-κB and MAPKs activation via the phosphatidylinositol 3-kinase signaling

The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

Mausumee Guha, Nigel Mackman · Journal of Biological Chemistry · 2002 · 789 citations · Full text

Life Sciences, Cell Biology, Immunology +17

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

Hua Yuan, Cynthia N. Perry, Chengqun Huang et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2008 · 263 citations · Full text

Life Sciences, Cardiology, Physiology +13

α-Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway

Weijian Zhang, Wei Hao, Tory M. Hagen et al. · Proceedings of the National Academy of Sciences · 2007 · 256 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Gastrodin Inhibits Expression of Inducible NO Synthase, Cyclooxygenase-2 and Proinflammatory Cytokines in Cultured LPS-Stimulated Microglia via MAPK Pathways

Ji-Nan Dai, Yi Zong, Lianmei Zhong et al. · PLoS ONE · 2011 · 215 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Modulation of the Phosphoinositide 3-Kinase Pathway Alters Innate Resistance to Polymicrobial Sepsis

David L. Williams, Chuanfu Li, Tuanzhu Ha et al. · The Journal of Immunology · 2004 · 174 citations · Full text

Life Sciences, Immunology, Pharmacology +15