Concepedia

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EVALUATION OF A NOVEL LIPID PRODRUG FOR INTRAOCULAR DRUG DELIVERY

DOI

16

Citations

0

References

1997

Year

İbrahim Taşkintuna, Alay Banker, Marisa Flores-Aguilar, GERMAINE BERGERONLYNN, Kathy A. Aldern, Karl Y. Hostetler, William R. Freeman
Retina

Abstract

Acyclovir diphosphate dimyristoylglycerol had prolonged antiviral activity against herpes simplex virus-1 retinitis in a rabbit model. This drug delivery system, modified to improve optical clarity, may allow long-acting intravitreal treatment of cytomegalovirus retinitis and other retinal diseases.